A psychic's girlfriend finds out that a lump on her back is a growing reincarnation of a 400 year-old demonic Native American spirit. Karen Tandy enters a San Franisco hospital suffering from a growing tumor on her back. To the doctors think it's a living creature, a fetus is being born inside the tumor. To fortune teller Harry Erskine says it's nothing until his client says strange languages, and kills herself by falling down a flight of stairs. And after one of the doctor's cut his hand. Erskine seeks help from another fortune teller Amelia Crusoe and her husband to find what is going on. When Karen's tumor gets larger, Dr. Snow begins to think it is a 400 year old Indian Spirit who wants revenge.